arxiv:2604.09782

Biomarker-Based Pretraining for Chagas Disease Screening in Electrocardiograms

Published on Apr 10

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Abstract

A biomarker-based pretraining approach using ECG feature extraction and ensemble modeling achieved competitive performance in Chagas disease detection from ECGs.

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Chagas disease screening via ECGs is limited by scarce and noisy labels in existing datasets. We propose a biomarker-based pretraining approach, where an ECG feature extractor is first trained to predict percentile-binned blood biomarkers from the MIMIC-IV-ECG dataset. The pretrained model is then fine-tuned on Brazilian datasets for Chagas detection. Our 5-model ensemble, developed by the Ahus AIM team, achieved a challenge score of 0.269 on the hidden test set, ranking 5th in Detection of Chagas Disease from the ECG: The George B. Moody PhysioNet Challenge 2025. Source code and the model are shared on GitHub: github.com/Ahus-AIM/physionet-challenge-2025

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